|  Arpanahi A, Brinkworth M, Iles D, Krawetz SA, Paradowska A, Platts AE, Saida M, Steger K, Tedder P, Miller D. Endonuclease-sensitive regions of human spermatozoal chromatin are highly enriched in promoter and CTCF binding sequences. Genome Res. 2009 Aug;19(8):1338-49. Epub 2009 Jul 7.
CMMG Newsletter, Winter 2011
News Archive |
Upcoming Seminars GuangJun Zhang, MD, PhD, Postdoctoral Research Associate, Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, "Fishing for cancer drivers by zebrafish-human comparative oncogenomics," on Tuesday, January 24, 2012 at 12:00 pm in 1358 Scott Hall.
Richard Gordon, PhD, Professor of Radiology, University of Manitoba, "Cause and effect in the interaction between Embryogenesis and the Genome," Thursday, January 26, 2012 at 12:00 pm in 2268 Scott Hall.
Center Announcements  Our former colleague and friend James Garbern, MD, PhD, who was Associate Professor of Neurology and of Molecular Medicine and Genetics from 1995 through 2010, died on November 11, 2011. He was 58. In 2010, Dr. Garbern accepted a position as Professor of Neurology at the University of Rochester Medical Center.
Dr. Garbern is survived by his wife Angela, and by his daughters Jessica and Stephanie. In lieu of flowers or gifts, Dr. Garbern’s family has asked that those who are interested send donations to the PMD Foundation in his memory, a cause so meaningful to Jim and one he worked so hard to find a cure for.
First year Molecular Biology and Genetics PhD student, Ze Zheng, placed first in the Oral Presentation's Session Three at Graduate Student Research Day held on Thursday, September 29, 2011.
Interested in becoming a genetic counselor? Join our webinar to learn more about the Wayne State University Genetic Counseling Graduate Program. Biology textbooks maintain that the main function of sex is to promote genetic diversity. But Henry Heng, Ph.D., associate professor in WSU's Center for Molecular Medicine and Genetics, says that's not the case. Heng and fellow researcher Root Gorelick, associate professor at Carleton University in Canada, propose that although diversity may result from a combination of genes, the primary function of sex is not about promoting diversity. Rather, it's about keeping the genome context – an organism's complete collection of genes arranged by chromosome composition and topology – as unchanged as possible, thereby maintaining a species' identity. "If sex was merely for increasing genetic diversity, it would not have evolved in the first place," said Heng. This is because asexual reproduction – in which only one parent is needed to procreate – leads to higher rates of genetic diversity than sex. More
A Wayne State University medical researcher has been awarded a $1.7 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health. Kezhong Zhang is assistant professor of molecular medicine and genetics and of immunology and microbiology in the School of Medicine at Wayne State. He will use the grant to explore how molecular elements in the body regulate the development of non-alcoholic fatty liver disease (NAFLD). More
Henry H.Q. Heng, PhD, Associate Professor of Molecular Medicine and Genetics and of Pathology, and Stephen Krawetz, PhD, Professor of Obstetrics and Gynecology and of Molecular Medicine and Genetics have been awarded the 2010 SOM Faculty Research Excellence Award. They join former Center honorees Russell Finley, Jr., Alexander Gow, Maik Huttemann, Jeffrey Loeb and Derek Wildman.
Leonard Lipovich, PhD, Assistant Professor of Molecular Medicine and Genetics and of Neurology, has been awarded an American Cancer Society Institutional Research Grant. Dr. Lipovich's award was for "Long non-protein-coding RNA (IncRNA) molecules in estrogen-responsive breast cancer." More
Monica Uddin, PhD, joins the Center as Assistant Professor of Molecular Medicine and Genetics and of Psychiatry and Behavioral Neurosciences. Her research interests include characterizing genomic phenotypes of mental illness; assessing gene-environment interactions in psychiatric disorders; and investigating developmental differences in the molecular contributions to mental illness. Prior to her appointment at Wayne State University, Dr. Uddin was Research Assistant Professor in the Center for Social Epidemiology and Population Health at the University of Michigan.
Abdul Abou-Samra, M.D., Ph.D., Professor of Internal Medicine, Division of Endocrinology and of Molecular Medicine and Genetics, has been awarded the prestigious 2011 WSU Board of Governors Faculty Recognition Award. This award is given annually to full-time faculty who have made outstanding contributions to scholarship and learning. More
Genetic Counseling Graduate Program announces Summer 2011 Open House. Center Graduate Research Assistant, Shruti Bagla and Neurology Postdoctoral Research Fellow, Fabien Dachet, PhD, both of Dr. Jeffrey Loeb's lab, placed first in the poster presentation at the Systems Biology Symposium held at the University of Michigan on April 4, 2011. The Mitochondrial Disease Clinic: The Center for Molecular Medicine and Genetics has partnered with the Wayne State University School of Medicine, the Detroit Medical Center, the Muscular Dystrophy Association and the Department of Neurology to establish a multidisciplinary Mitochondrial Disease Clinic (MDC). The primary goal of the MDC is to diagnose and treat patients with dieases in which mitochondrial dysfunction plays a major role. These include rare conditions, such as Leber's Hereditary Optic Neuropathy and Kearns-Sayre Syndrome, as well as more common diseases such as muscular dystrophies and spinocerebellar ataxias. In addition to its clinical role, the MDC will also integrate basic research on mitochondrial function in human disease, carried out within the Center for Molecular Medicine and Genetics. Since mitochondrial dysfunction also occurs in a number of important conditions such as stroke and diabetes, the research component of the MDC will be relevant to these common conditions as well. The physicians and scientists in the MDC will thus provide a personalized approach to patient health enhanced by a close collaboration of clinicians and basic scientists working toward the same ends. More information regarding the clinic can be found at http://www.dmc.org/mitomed. Recent Publications of Center Faculty Lipovich L, Johnson R, and Lin CY. MacroRNA underdogs in a microRNA world. (invited review article) Biochimica et Biophysica Acta 1799: 597-615, 2010. More.... Laing S, Wang G, Briazova T, Zhang C, Wang A, Zheng Z, Gow A, Chen AF, Rajagopalan S, Chen LC, Sun Q, Zhang K. Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues. Am J Physiol Cell Physiol 299(4):C736-749, 2010. More.... |
